Detroit Lions
| Casey Fitzsimmons | TE | Concussion | Out |
| Andre Fluellen | DE | Groin | Doubtful |
| Matthew Stafford | QB | left Shoulder | Doubtful |
| Joe Cohen | DT | Knee | Questionable |
| Daniel Loper | G | Back | Questionable |
| Eric Fowler | WR | Knee | Probable |
| William James | CB | Neck | Probable |
| Louis Delmas | S | Ankle | Probable |
| Nick Harris | P | left Knee | Probable |
| Grady Jackson | DT | Knee | Probable |
| Kalvin Pearson | S | Hamstring | Probable |
| Ernie Sims | LB | Hamstring | Probable |
| Dewayne White | DE | Toe | Probable |
Baltimore Ravens
| Mark Clayton | WR | Knee | Doubtful |
| David Hale | G | Head | Doubtful |
| Ed Reed | S | Groin | Doubtful |
| L.J. Smith | TE | Ankle | Doubtful |
| Jared Gaither | T | Foot | Questionable |
| Terrell Suggs | LB | Knee | Questionable |
| Jarret Johnson | LB | Back | Questionable |
| Brandon McKinney | DT | Back | Questionable |
| Billy Cundiff | K | Head | Probable |
| Joe Flacco | QB | Knee | Probable |